Mdk Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comMdk Polyclonal Antibody for Rat(Rattus norvegicus)

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Mdk (Gene name),

Midkine (Protein name ), MK_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mdk;

Protein name:

Midkine(MK);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer (By similarity). Interacts with ALK.

Function:

Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

140

Sequence:

50:

100:

140:

QGTLKKARYN | AQCQETIRVT | KPCTSKTKSK | AKAKKGKGKD |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9R1S9

UniGene:

Rn.17447

Pfam:

PF01091

KEGG:

rno:81517

Uniprot:

Q9R1S9

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ELISA Kit for Rat MK

Cat.:

E0631m

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MSDS:

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Packing:

96T

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ELISA Kit for Rat MK

Cat.:

E0631h

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Packing:

96T

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ELISA Kit for Rat MK

Cat.:

E0631r

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96T

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CLIA Kit for Rat MK

Cat.:

U0631r

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MSDS:

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Packing:

96T

CLIA Kit for Rat MK

Cat.:

U0631h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat MK

Cat.:

U0631m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Rat MK

Cat.:

P0631Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MK

Cat.:

P0631Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MK

Cat.:

P0631Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat MK

Protein for Rat MK

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Neointima formation in a restenosis model is suppressed in midkine-deficient mice."
Horiba M. , Kadomatsu K. , Nakamura E. , Muramatsu H. , Ikematsu S. , Sakuma S. , Hayashi K. , Yuzawa Y. , Matsuo S. , Kuzuya M. , Kaname T. , Hirai M. , Saito H. , Muramatsu T.
J. Clin. Invest.105:489-495(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;INDUCTION
strain: Sprague-Dawley.
tissue: Kidney.
2.

"Midkine is expressed early in rat fetal adrenal development."
Dewing P. , Ching S.T. , Zhang Y.-H. , Huang B.-L. , Peirce R.M. , McCabe E.R.B. , Vilain E.
Mol. Genet. Metab.71:616-622(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;DEVELOPMENTAL STAGE
strain: Sprague-Dawley.
tissue: Fetal adrenal gland.
3.

"Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins."
Kretschmer P.J. , Fairhurst J.L. , Decker M.M. , Chan C.P. , Gluzman Y. , Boehlen P. , Kovesdi I.
Growth Factors5:99-114(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;DEVELOPMENTAL STAGE

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